Stereo-chemistry of Metallic Compounds
The relationship between stereochemistry and spin state has led us to formulate simple rules to predict the geometries of 4 & 6 -coordinated transition metals. The reason that isomers are so important in drug design is that normally, just one particular isomer is effective in treating the condition. The branch of chemistry that is concerned with the spatial arrangements of atoms in molecules and with chemical and physical effects of these arrangements. There are two geometric isomers possible for this composition: Cis and Trans. The facial isomer gets its name because all three chlorides are coordinated on one face of the octahedron. The merisomer (short for "meridional“) has the three chloride ions coordinated in an exceedingly that has the metal ion.
-  Molecular chirality and enantiomers
-  Transition Metal Complexes as Drugs
-  Optical Isomerism
-  Stereo chemistry of reactions of Transition metal-Carbon Sigma bonds