Drug,Pharmaceutical Chemistry & Chemistry of Transition Elements

Pharmaceutical chemistry is the study of medicine, and it involves drug development. Pharmaceutical chemistry involves cures and remedies for disease, analytical techniques, pharmacology, metabolism, quality assurance, and drug chemistry.Pharmaceutical chemistry also includes other branches of study such as pharmacokinetics, pharmacodynamics, and drug metabolism. These are important for learning the consequences that drugs possess the body. By discovering and structurally characterizing compounds with medicative activity, chemists’ surface measure ready to style new medicine with increased efficiency and shrivelled adverse side effects.

The transition metals are the metallic elements that mean a bridge, or transition, between the two sides of the table. They have partially filled d orbitals.

Properties of transition metals:

  • Metals almost all: HARD, STRONG, High melting and boiling point
  • Conduct heat & electricity
  • Form Alloys
  • Show variable oxidation states
  • Form paramagnetic species as a result of partially filed shells.

Most transition metals form also one oxidation state. Transition metals demonstrate a wide range of chemical behaviours. Some transition metals are strong reducing agents, whereas others have very low reactivity. The elements titanium, manganese, zirconium, vanadium, and chromium too have abundances in more than of 100 grams (3.5 ounces) per ton. Some of the most important and useful transition elements have very low crustal abundances—e.g., tungsten, platinum, gold, and silver.

 

  •  Drug design
  •  Hit to lead and lead optimization
  •  Process chemistry and development
  •  Metabolonomics of new pharmaceutical agents
  •  High performance liquid chromatography
  •  Genomics and Proteomics
  •  Variable oxidation state
  •  Early and Late transition metals
  •  Co Ordination numbers

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